CrossRefPubMed 12. Korkolopoulou P, Saetta AA, Levidou G, Gigelou F, Lazaris A, Thymara I, Scliri M, Bousboukea K, Michalopoulos NV, Apostolikas N, Konstantinidou A, Tzivras M, Patsouris E: c-FLIP expression in colorectal carcinomas: association with Fas/FasL expression and prognostic implications. Histopathology 2007, 51: 150–6.CrossRefPubMed 13. Brummelkamp TR, Bernards R, Agami R: A system for stable expression of short interfering RNAs in mammalian cells. Science 2002, 296: 550–3.CrossRefPubMed
14. Flahaut M, Mühlethaler-Mottet A, Auderset K, Bourloud KB, Meier R, Popovic MB, Joseph JM, Gross N: Persistent inhibition of FLIP(L) expression by lentiviral small hairpin RNA delivery restores death-receptor-induced apoptosis in neuroblastoma cells. Apoptosis 2006, 11: 255–63.CrossRefPubMed selleck compound 15. Grigioni WF, D’Errico A, Bacci F, Gaudio M, Mazziotti A, Gozzetti G, Mancini AM: Primary liver neoplasms: evaluation of proliferative index using MoAb Ki-67. J Pathol 1989, 158: 23–9.CrossRefPubMed 16. Yang X, Khosravi-Far R, Chang HY, Baltimore D: Daxx, a novel Fas-binding protein that activates JNK and apoptosis. Cell 1997, 89: 1067–76.CrossRefPubMed 17. Jäckel MC: Genetic PCI-32765 mw control of programmed cell death (apoptosis): prospects for biological tumor staging? HNO 1998, 46: 614–25.CrossRefPubMed 18. Okano H, Shiraki K, Inoue H, Kawakita T, Yamanaka T, Deguchi M, Sugimoto K, Sakai T, Ohmori S, Fujikawa K, Murata K, Nakano T: Cellular
FLICE/caspase-8-inhibitory EGFR inhibitor protein as a principal regulator of cell death and survival in human hepatocellular carcinoma. Lab Invest 2003, 83: 1033–43.CrossRefPubMed 19. Kataoka T, Budd RC, Holler N, Thome M, Martinon F, Irmler M, Burns K, Hahne M, Kennedy N, Kovacsovics M, Tschopp J: The caspase-8 inhibitor FLIP promotes activation of NF-kappaB and Erk signaling pathways. Curr Biol 2000, 10: 640–8.CrossRefPubMed 20. Kreuz S, Siegmund D, Scheurich P, Wajant H: NF-kappaB inducers upregulate cFLIP, a cycloheximide-sensitive
inhibitor of death receptor signaling. Mol Cell Biol 2001, 21: 3964–73.CrossRefPubMed 21. Lee SH, Kim HS, Kim SY, Lee YS, Park WS, Kim SH, Lee JY, Yoo NJ: Increased expression of FLIP, an inhibitor of Fas-mediated apoptosis, in stomach cancer. APMIS 2003, 111: 309–14.CrossRefPubMed 22. Thomas RK, Kallenborn A, Wickenhauser C, Schultze JL, Draube A, Vockerodt M, Re D, Diehl V, Wolf J: Constitutive expression of c-FLIP in Hodgkin and Reed-Sternberg cells. Am J Pathol 2002, 160: 1521–8.PubMed 23. Jönsson G, Paulie S, Grandien A: High level of c-FLIP correlates with resistance to death receptor-induced apoptosis in bladder carcinoma cells. Anticancer Res 2003, 23: 1213–8.PubMed 24. Korkolopoulou P, Goudopoulou A, Voutsinas G, Thomas-Tsagli E, Kapralos P, Patsouris E, Saetta AA: c-FLIP expression in bladder urothelial carcinomas: its role in resistance to Fas-mediated apoptosis and clinicopathologic correlations. Urology 2004, 63: 1198–204.CrossRefPubMed 25.