, 2011). This book, together with the Dictionary of the Fungi (Kirk et al., 2008), gives an overview of the taxonomic status of all genera of filamentous fungi. As for the current taxonomy of fungi, we have used the references and documentation provided NVP-BEZ235 concentration by the International Commission on the Taxonomy of Fungi (ICTF) on their website (http://www.fungaltaxonomy.org/) and the Mycobank initiative (Crous et al., 2004), as well as expert groups on invasive fungal infections and taxonomic issues (Mycoses Study Group—http://www.doctorfungus.org/). Although they have been used since ancient times in fermentation processes without

any identified major concern, recent discovery of rare events of adverse effects caused by microorganisms in fermented foods raise uncertainty about the level of risk, depending either on the food matrix or the susceptibility of the host (Gasser, 1994 and Miceli et al., 2011). Commensal bacteria have been described to cause infections in patients with underlying disease (Berg and Garlington, 1979, Berg, 1985 and Berg, 1995). Owing to its natural presence

in different sites of the selleck screening library human body and in fermented food products, the genus Lactobacillus has gained particular attention. Lactobacillus infections occur at a very low rate in the generally healthy population—estimated 0.5/1 million per year ( Borriello et al., 2003 and Bernardeau et al., 2006). As stated in two reviews of Lactobacillus infections: “Underlying Resveratrol disease or immunosuppression are common features in these cases, whereas infection in previously healthy humans is extremely rare”

( Aguirre and Collins, 1993). “Lactobacillus bacteraemia is rarely fatal per se but serves as an important marker of serious underlying disease” ( Husni et al., 1997). Sporadic infections have been reported in immuno-compromised patients. The underlying problems have mainly been central venous catheter (CVC) in place, metabolic disorders, organ failure, or invasive procedures such as dental work ( Axelrod et al., 1973 and Liong, 2008). Infections by other bacterial species used as MFC are also extremely rare ( Horowitz et al., 1987, Barton et al., 2001, Mofredj et al., 2007 and Leuschner et al., 2010). Infections with the commonly used yeast and mold species are rare events as well (Enache-Angoulvant and Hennequin, 2005). Most of the infections are due to opportunistic pathogens not recognized as MFC and affect immuno-compromised patients and hospitalized patients (Winer-Muram, 1988, Jacques and Casaregola, 2008 and Miceli et al., 2011). Biogenic amine formation in fermented foods by lactic acid bacteria (LAB) has recently been reviewed (Spano et al., 2010). Following food poisoning outbreaks (Sumner et al., 1985), metabolic pathways have been elucidated (Straub et al., 1995) and screening procedures proposed to limit the level of production (Bover-Cid and Holzapfel, 1999 and Bover-Cid et al., 2000).