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“Background Lung cancer develops in more than 200,000 people and causes more than 160,000 deaths each year; non-small cell lung cancer (NSCLC) is the most common type of lung cancer. Cisplatin doublets remain the cornerstone of treatment[1]; however, the median overall survival remains less than one year despite multiple combinations of third generation cytotoxic drugs and novel targeted therapies. Anticancer drug regimens selected based on newly identified predictive factors may lead to an improvement in outcomes.