One limitation of the current study is the unknown variations below in the patient population. However, the prostate gland is not considered to exhibit large anatomical variations among patients, thereby allowing us to perform an intercomparison of the different TPSs. Another concern is the different photon energies employed by the three TPSs. In conclusion, the three TPSs provided virtually equivalent early clinical outcomes and toxicities even though they exhibited significant TPS-specific delivery parameter variations.Late outcomes and toxicities need to be studied with a longer follow-up period.Conflict of InterestsThe authors declare that they have no conflict of interests.

Drug addiction is a complex mental health problem that is often associated with difficulties in various life domains such as unemployment, homelessness, relational conflicts, problems with the courts, and psychiatric comorbidity [1, 2]. While some of these problems certainly evolve from the abuse of substances, many eventual addicts suffer from these problems prior to the onset of their drug use [3]. In both cases, drug addiction has generally been treated as an acute condition during brief episodes of residential care or several months of outpatient treatment, where the primary if not exclusive focus has been on abstinence to the exclusion of other concerns [4]. In contrast, addiction is increasingly regarded as a chronic relapsing disorder where recovery is possible [5], but often the one that requires intensive or even multiple treatment episodes and/or strong personal or community resources.

A continuing care approach is needed to initiate and maintain recovery [6, 7]. The recovery movement focuses on individuals’ perceived needs and objectives and sees abstinence as a potential resource, but not as a prerequisite, for recovery [8�C10]. A recovery-oriented approach in addiction research implies attention for the evolutions on various life domains and individuals’ subjective well being as well as the adoption of a longitudinal perspective to understand the complexity of individuals’ substance use careers and recovery processes [11]. A wide range of treatment and support services are available for persons with alcohol or drug addiction problems: Dacomitinib detox programs, drug-free outpatient treatment, methadone maintenance therapy, long-term residential treatment programs, and harm reduction services.