Results. There were significant differences in OQLQ scores among the 4 groups (P < .001). When comparing the presurgery group to other groups: significant differences were found with postsurgery, Dec-surg, and control subjects (P < .001). The Dec-surg group showed no significant differences with postsurgery and control groups.

Conclusions. Orthognathic surgery has a positive impact on patients’ QOL. The condition-specific OQLQ showed better discriminator ability than

the generic SF-36, although both measures provide an effective combination to evaluate QOL in patients with dentofacial deformities. More emphasis is required to understand emotional and psychosocial status of patients in addition to their esthetic PFTα cost and functional

needs. (Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2009; 107: 49-55)”
“Dilated cardiomyopathy (DCM) is characterized by chamber dilation and cardiac dysfunction. Because of the poor prognosis, models are needed for the investigation of and development of new therapeutic approaches, as well as stem cell therapy. Doxorubicin (DOX), used as chemotherapeutic agent, is reported to be cumulative cardiotoxic causing DCM. The aim of the study was to investigate the onset of systolic dysfunction using echocardiography in rabbits receiving two different doses of DOX (1 mg/kg twice a week and 2 mg/kg once a week). Twenty rabbits were treated with doxorubicin in two different doses for 6 weeks and compared with a control group treated with NaCl click here 0.9%. The effect of doxorubicin on the

myocardium was investigated with histological analysis and scanning electron microscopy of left ventricle (LV), as Well as in the interventricular septum (IVS) and right ventricle (RV). The results showed a high mortality rate for rabbits receiving 2 mg/kg once a week. A significant reduction in systolic function was present in animals treated with DOX after 6 weeks, with decreased ejection fraction and shortening fraction. Histology and electron microscopy revealed vacuolization, intracytoplasmic granulation, necrosis and interstitial fibrosis in LV, as well as in the IVS and RV. Doxorubicin induced changes are present in the LV, RV and IVS, and the administration at the dose of 1 mg/kg twice a week Protein Tyrosine Kinase inhibitor for only 6 weeks is safe and sufficient to induce DCM in rabbits. (C) 2012 Elsevier Ltd. All rights reserved.”
“The hydrolysis of poly(ethylene terephthalate) (PET) was studied using ionic liquid 1-n-butyl-3-methylimidazolium chloride ([Bmim][Cl]) as solvent and acid-functionalized ionic liquid 1-methyl-3-(3-sulfopropyl)-imidazolium hydrogen sulfate ([HSO(3)-pmim][HSO(4)]) as catalyst. The effects of temperature, time, and dosages of solvent and catalyst on hydrolysis results were examined. Under the optimum conditions of m(PET) m(H(2)O) : m([Bmim][Cl]) : m([HSO(3)-pmim][HSO(4)]) = 3 4 : 6 : 0.6, reaction temperature 170 degrees C and time 4.