Samples from IDUs were tested at the Referral laboratory of Sindh

Samples from IDUs were tested at the Referral laboratory of Sindh Tipifarnib cancer AIDS Control Program by ELISA Methods using Bio-Rad Monolisa Antigen-antibody Coombo test kits. Data were recorded and analyzed using the Stata Software Version 11 (StataCorp, College Station, TX, USA). We categorized the age using 10-year groups from 21�C30, 31�C40, and 41�C50years old. The means between groups were compared using the independent sample t test and analysis of variance (ANOVA) with bonferroni adjustments for multiple comparisons was done. We explored the association between age group, gender and risk group by using the logistic regression model. Health-care worker group was taken as a reference category when investigating the relationship between risk group and hepatitis B and C.

As this group may have prevalence of hepatitis B and C approximate to the background population or may be slightly higher than that. We constructed two different models for hepatitis B and Hepatitis C. Age was found to be significant on univariate analysis and was therefore included in the final multivariate model Inhibitors,Modulators,Libraries to make appropriate adjustments. The level of significance was set at 95% (p value<0.05). Results We screened 4202 subjects for hepatitis B and C, out of these, 3637 were males and 565 were females. Female participants were only available to participate in the health care workers group. The mean age of participants was 41.07��6.06. On average, females Inhibitors,Modulators,Libraries were significantly (p<0.001) younger than males (38.6 versus 41.4years). There was no significant difference of age between those who were hepatitis B reactive (42.

1��6.09years) compared with non-reactive Inhibitors,Modulators,Libraries subjects (40.9��5.97years) (Table (Table11). Table 1 Baseline characteristics of subjects screened for Hepatitis B and C A total of 681 participants were reactive either with hepatitis B or C. Inhibitors,Modulators,Libraries One hundred and thirty three (3.17%) were hepatitis B reactive and 548 (13.0%) were diagnosed with hepatitis C. The proportion of hepatitis B reactive cases was fairly similar across different age categories; however the frequency of hepatitis C reactive cases was significantly higher among individuals of ages between 41 to 50years compared to the individuals of age 21�C30years (p-value<0.001) (Figure (Figure11). Figure 1 Hepatitis Inhibitors,Modulators,Libraries B and C prevalence between different age groups. Mean age of prisoners and IDUs screened in this study was significantly higher (p<0.

001) compared with health care workers and security personnel. Difference observed in the frequency of hepatitis C across different age categories was explored after adjusting the effect of the risk group. Prevalence of hepatitis B and C differed significantly between groups. Prevalence of hepatitis B and C was Batimastat lowest among HCWs (hepatitis B 1.0%, hepatitis C 2.9%), while prevalence of hepatitis B and C was highest among IDUs (hepatitis B 5.7%, hepatitis C 68.3). Prevalence of hepatitis B was 1.

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