A questionnaire with demographic information, clinical Selleck MEK inhibitor signs and symptoms, laboratory and radiographic findings was completed for each patient. The information required for calculating the pneumonia severity index and CURB-65 were extracted from the medical records. The patients’ clinical outcome was also recorded within a month after admission.
Results:
We studied 200 patients with community-acquired pneumonia (122 men, 78 women). The sensitivity and specificity of CURB-65 in predicting mortality were 100% and 82.3%, respectively. As for pneumonia severity index, the rates were 100% and 75%, respectively. The sensitivity and specificity rates of CURB-65 and pneumonia severity index in predicting mortality and need for ICU admission were 96.7% and 89.3%, and 90% and 78.7%, respectively.
Conclusion: CURB-65 seems to be the preferred method to predict
mortality and need for ICU admission in patients with community-acquired pneumonia. Despite their comparable specificity and sensitivity, CURB-65 is much easier to implement. (C) 2013 Elsevier Editora Ltda. All rights reserved.”
“Background: Although recreational gambling is prevalent and co-occurs with substance abuse/dependence, few studies have investigated the relationship between the two.
Methods: Logistic regression analyses were performed on data from a nationally representative sample from the Gambling Impact and Behavior Study.
Results:
Substance-abusing recreational gamblers, as compared Selleckchem Proteasome inhibitor to non-substance-abusing ones, differed in gambling motivations, began gambling at earlier ages, reported heavier gambling, and preferred and performed strategic forms of gambling.
Conclusions: As compared with non-substance-abusing gamblers, substance-abusing gamblers demonstrated different gambling profiles including heavier gambling. These findings suggest the need for additional research on whether and how substance use might promote gambling and vice versa. (C) 2008 Elsevier Ireland Ltd. All rights reserved.”
“Background: The occurrence selleck chemical of syphilis and HIV-1 infections during pregnancy are major risks to the fetus due to mother-to-child transmission (MTCT).
Objectives: To determine peripartum seroprevalence and risk factors of syphilis and HIV-1 infection among pregnant women in Salvador, Brazil, and the rate of HIV-1 MTCT.
Methods: Cross-sectional study of pregnant women who were admitted for delivery in a reference maternity hospital between May 2008 and March 2009 was conducted. Women were screened for HIV-1 infection and syphilis, and interviewed regarding demographic, behavioral and obstetric data. Newborns to HIV-infected mothers were tested by b-DNA and DNA-PCR to detect HIV-1.
Results: A total 3300/8516 women were evaluated. Mean age was 25.8 +/- 7.3 years. HIV-1 and syphilis seroprevalence rates were 0.