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“Introduction Since Oparin’s ideas (1924; 1938) and Miller-Urey’s famous experiment (1953) on the prebiotic synthesis of amino acids, one of the main problems of prebiotic chemistry is to “re-invent” the plausible range of indispensable physical-chemical boundary requirements that would enable the emergence of stable and replicable molecules on the primordial Earth (Eschenmoser 2003).