On the basis of these studies, simple structured solar cells, consisting of ZnO: Al thin film (80 nm)/highly doped p-type nanocrystalline silicon films with a series of thickness/n-type (100) silicon wafer substrates, were fabricated and used to assess the performance of p-type nanocrystalline silicon films. The conversion efficiency increases with decreasing the film thickness of p-type nanocrystalline silicon thin films and achieves the largest click here value of 8.2% when the thin film thickness
is near 90 nm. (C) 2011 American Institute of Physics. [doi:10.1063/1.3642983]“
“Purpose: To prospectively evaluate in vivo noninvasive monitoring of antibiotic therapy in experimental infectious arthritis by imaging macrophages by using magnetic Autophagy Compound Library chemical structure resonance (MR) imaging enhanced with ultrasmall superparamagnetic iron oxide (USPIO) particles.
Materials and Methods: The institutional review committee on animal care approved the experimental protocol. Unilateral knee infection was induced by intra-articular injection of Staphylococcus aureus in 12 rabbits. Each rabbit underwent MR imaging before and after injection of USPIO particles, as well as before and after injection of gadoterate meglumine. All 12 of the animals were imaged during the acute phase of infection. Half were then sacrificed to obtain histopathologic samples, and the other half were imaged a second time after antibiotic
treatment. MR imaging data were analyzed and compared with bacteriologic and histopathologic findings.
Results: In acute infections, intense synovitis with marked signal intensity increase of the synovium on gadoterate dimeglumine-enhanced fat-suppressed T1-weighted images was observed in all animals PCI-34051 and was associated with areas of signal intensity loss within the infected synovium on USPIO-enhanced T2*-weighted gradient-echo images, reflecting an intense infiltration of USPIO-loaded macrophages. After antibiotic treatment and histologic evidence of
healing infection, less synovial signal intensity loss was seen (P = .03). In contradistinction, the signal intensity increase on gadoterate dimeglumine-enhanced fat-suppressed T1-weighted images remained unchanged.
Conclusion: In contrast to conventional MR imaging performed by using extracellular contrast agents, USPIO-enhanced macrophage MR imaging can demonstrate resolution of experimental bacterial joint infection. (C)RSNA, 2011″
“HCV genotypes 2- or 3-infected patients with a rapid virological response (RVR) to therapy with pegylated interferon and ribavirins who have a low viral load, noncirrhotic and nonobese may be considered for a shorter course of treatment. However, no studies have assessed host-viral factors associated with relapse in genotype 2 and 3 separately. Accordingly, we assessed whether 12 weeks of pegylated interferon and ribavirin was an optimized regimen for treatment of HCV genotype 2 and 3 with positive predictors of response.